Isabel Almeida, MD, PhD

Integrated PhD Researcher

orcid.org/0000-0002-8867-1540

Academic degrees:

PhD in Medical Sciences

Medical Doctor

Current Positions:

• Assistente Hospitalar Graduado, CHP-HSA

Research interests:

• Dysregulation of immune system in systemic sclerosis development
• Immune system functioning in autoimmune diseases and allergies development
• Vascular complication in systemic sclerosis
  

Research area keywords:

Immunology; Autoimmune diseases; Systemic Sclerosis; Vascular functioning

Major Scientific Achievements:

• Endostatin may be an early marker for systemic sclerosis development whilst angiostatin is a marker for late disease onset being associated with lung affection severity
• P-selectin and VCAM-1 may be early disease markers throughout the course of systemic sclerosis
• CD8+ T lymphocytes and NK cells, may play a relevant role in Sistemic Sclerosis pathogenesis, operating at different phases of disease development and/or at different organs.
  

Selected publications:

1. Almeida I, Oliveira Gomes A, Lima M, Silva I, Vasconcelos C. Different contributions of angiostatin and endostatin in angiogenesis impairment in systemic sclerosis: a cohort study. Clin Exp Rheumatol. 2016 Sep-Oct;34 Suppl 100(5):37-42.
2. Almeida I, Ferrão C, Oliveira JC, Silva I, Vasconcelos C, Lima M. Cell adhesion molecules in systemic sclerosis – results from a Portuguese Cohort. Journal of Autoimmunity & Research. 2017; 4(2): 1021
3. Almeida I, Silva SV, Fonseca AR, Silva I, Vasconcelos C, Lima M. T and NK Cell Phenotypic Abnormalities in Systemic Sclerosis: a Cohort Study and a Comprehensive Literature Review. Clin Rev Allergy Immunol. 2015 Dec;49(3):347-69. doi: 10.1007/s12016-015-8505-8
4. Carvalho C, Marinho A*, Leal B, Bettencourt A, Boleixa D, Almeida I, Farinha F, Costa PP, Vasconcelos C, Silva BM. Association between vitamin D receptor (VDR) gene polymorphisms and systemic lupus erythematosus in Portuguese patients.Lupus. 2015 Jul;24(8):846-53.
5. Bettencourt A, Carvalho C, Leal B, Brás S, Lopes D, Martins da Silva A, Santos E, Torres T, Almeida I, Farinha F, Barbosa P, Marinho A, Selores M, Correia J, Vasconcelos C, Costa PP, da Silva BM. The Protective Role of HLA-DRB1(∗)13 in Autoimmune Diseases. J Immunol Res. 2015; 2015:948723.
   

MSc thesis supervision (Concluded):

• Rafael Almeida Avaliação dos conhecimentos sobre o VIH/SIDA da população geral. Mestrado Integrado em Medicina, ICBAS-UPorto. Orientadora
• Sílvia Cunha. Avaliação dos conhecimentos sobre o VIH/SIDA dos doentes na Consulta de Imunologia do CHP- HSA. Mestrado Integrado em Medicina, ICBAS-UPorto. Orientadora
• Pedro Mondim. Prioritizing Acute Coronary Syndromes with the Manchester Triage System. Mestrado Integrado em Medicina, ICBAS-UPorto. Orientadora
• Manuela Bertão. Estudo de prevalência do Fenómemo de Raynaud no grande Porto. Mestrado Integrado em Medicina, ICBAS-UPorto. Co-Orientadora
• Liliana Gomes. Diagnostico precoce da Esclerose Sistémica – a evolução de conceitos. Mestrado Integrado em Medicina, ICBAS-UPorto. Co-Orientadora
• Ana Gonçalves. Relatório de estagio no Serviço de Urgência. Mestrado Integrado em Medicina, ICBAS-UPorto. Co-Orientadora
• Mariana Certal. The link between Autoimmune and Allergic Diseases: a systematic review. Mestrado Integrado em Medicina, ICBAS-UPorto. Co-Orientadora