Manuel Melo Pires, MD, PhD

Integrated PhD Researcher

orcid.org/0000-0002-0046-6455

Academic degrees:

PhD

Medical Doctor

Current Positions:

• Head of Neuropathology unit from Hospital Santo António – Centro Hospitalar do Porto
• Professor at ICBAS-UPorto

Research interests:

• Clinical and neuropathological characterization of Alzheimer’s disease
• Neuropathological characterization of dementia and ageing
• Histopatological features of epilepsy
• Clinical and histopathological characterization of myopathies

Research area keywords:

Neuropathology, Dementia, Epilepsy, Alzheimer’s Disease, Movement Disorders

Selected publications:

1. Blumcke I, Spreafico R, Haaker G, Coras R, Kobow K, Bien CG, Pfäfflin M, Elger C, Widman G, Schramm J, Becker A, Braun KP, Leijten F, Baayen JC, Aronica E, Chassoux F, Hamer H, Stefan H, Rössler K, Thom M, Walker MC, Sisodiya SM, Duncan JS, McEvoy AW, Pieper T, Holthausen H, Kudernatsch M, Meencke HJ, Kahane P, Schulze-Bonhage A, Zentner J, Heiland DH, Urbach H, Steinhoff BJ, Bast T, Tassi L, Lo Russo G, Özkara C, Oz B, Krsek P, Vogelgesang S, Runge U, Lerche H, Weber Y, Honavar M, Pimentel J, Arzimanoglou A, Ulate-Campos A, Noachtar S, Hartl E, Schijns O, Guerrini R, Barba C, Jacques TS, Cross JH, Feucht M, Mühlebner A, Grunwald T, Trinka E, Winkler PA, Gil-Nagel A, Toledano Delgado R, Mayer T, Lutz M, Zountsas B, Garganis K, Rosenow F, Hermsen A, von Oertzen TJ, Diepgen TL, Avanzini G; EEBB Consortium. Histopathological Findings in Brain Tissue Obtained during Epilepsy Surgery. N Engl J Med. 2017 Oct 26;377(17):1648-1656. doi: 10.1056/NEJMoa1703784.
2. Taipa R, Pereira C, Reis I, Alonso I, Bastos-Lima A, Melo-Pires M, Magalhães M. DJ-1 linked parkinsonism (PARK7) is associated with Lewy body pathology. Brain. 2016 Jun;139(Pt 6):1680-7. doi: 10.1093/brain/aww080. Epub 2016 Apr 16.
3. Brandão E, Melo-Pires M, Veira C. Relapsing-remitting tumefactive demyelination. JAMA Neurol. 2014 Mar;71(3):366-7. doi: 10.1001/jamaneurol.2013.5.
4. Taipa R, Tuna A, Damásio J, Pinto PS, Cavaco S, Pereira S, Milterberger-Miltenyi G, Galimberti D, Melo-Pires M. Clinical, neuropathological, and genetic characteristics of the novel IVS9+1delG GRN mutation in a patient with frontotemporal dementia. J Alzheimers Dis. 2012;30(1):83-90. doi: 10.3233/JAD-2012-112084.
5. Maia LF, Magalhães R, Freitas J, Taipa R, Pires MM, Osório H, Dias D, Pessegueiro H, Correia M, Coelho T. CNS involvement in V30M transthyretin amyloidosis: clinical, neuropathological and biochemical findings. J Neurol Neurosurg Psychiatry. 2015 Feb;86(2):159-67. doi: 10.1136/jnnp-2014-308107.