Isabel Fonseca, PhD

Integrated PhD Researcher

orcid.org/0000-0001-8984-1751

Academic degrees:

PhD

Positions:

• Renal Nutritionist at Department of Nephrology and Kidney Transplantation of Centro Hospitalar do Porto, Porto
• Clinical Nutritionist at Corino de Andrade Unit of Centro Hospitalar do Porto, Porto
• Responsible for the Scientific Review Committee at Research Coordinating Office - Department of Teaching, Training and Research of Centro Hospitalar do Porto, Porto
• Invited Biostatistics Teacher of “Introduction to Clinical Research” in the course of Medicine of Institute of Biomedical Sciences Abel Salazar, University of Porto
• Biostatistician at Corino de Andrade Unit of Centro Hospitalar do Porto, Porto

Research interests:

• Current research areas of interests are related with kidney disease, dialysis and kidney transplantation, namely biomarkers of graft dysfunction and predictors of patient and graft outcomes; survival analysis and prognostic models. Also interested in clinical nutrition and nutritional evaluation methodology; and in Transthyretin familial amyloid polyneuropathy (TTR-FAP) Val30Met.

Research area keywords:

Kidney transplantation, Dialysis and Kidney Disease, Clinical nutrition; nutritional evaluation methodology, Statistical methods in medical research, Survival analysis; prognostic models; competing events analysis, Clinical epidemiology

Selected publications:

1. Fonseca I, Reguengo H, Oliveira JC, Martins LS, Malheiro J, Almeida M, Santos J, Dias L, Pedroso S, Lobato L, Henriques AC, Mendonça D. A triple-biomarker approach for the detection of delayed graft function after kidney transplantation using serum creatinine, cystatin C, and malondialdehyde. Clin Biochem 2015; 48(16-17): 1033-8. PMID: 26162495
2. Fonseca I, Teixeira L, Malheiro J, Martins S, Dias L, Castro Henriques A, Mendonça D. The effect of delayed graft function on graft and patient survival in kidney transplantation: an approach using competing events analysis. Transpl Int 2015; 28(6): 738-50. PMID: 25689397
3. Fonseca I, Oliveira JC, Santos J, Malheiro J, Martins LS, Almeida M, Dias L, Pedroso S, Lobato L, Henriques AC, Mendonça D. Leptin and adiponectin during the first week after kidney transplantation: biomarkers of graft dysfunction? Metabolism 2015; 64(2): 202-7. PMID: 25458832
4. Fonseca I, Henrique H, Almeida M, Dias L, Martins LS, Pedroso S, Santos J, Lobato L, Henriques AC, Mendonça D. Oxidative stress in kidney transplantation: Malondialdehyde is an early predictive marker of graft dysfunction. Transplantation. 2014; 97(10): 1058-65. PMID: 24406454
5. Fonseca I, Oliveira JC, Almeida M, Cruz M, Malho A, Martins LS, Dias L, Pedroso S, Santos J, Lobato L, Henriques AC, Mendonça D. Neutrophil gelatinase-associated lipocalin in kidney transplantation is an early marker of graft dysfunction and is associated with one-year renal function. J Transplant. 2013; doi: 10.1155/2013/650123. Epub 2013 Oct 31. PMID: 24288591

• Josefina Santos, PhD Research Project on Medical Sciences of - Institute of Biomedical Sciences Abel Salazar, University of Porto, Porto, Chronic kidney disease in the elderly: understanding outcomes and trajectories of kidney function decline, towards an individualized care”, 2020

MSc thesis supervision (concluded):

• Bárbara Marques, Master Thesis in Clinical Nutrition, Faculty of Nutrition and Food Sciences, University of Porto, “Protein intake estimation of patients on hemodialysis and peritoneal dialysis: comparison between the values obtained by dietary survey and calculation of the protein equivalent of appearance of urea nitrogen (PNA)”, (completed on June/2015)